通过变性梯度凝胶电泳快速检测高度多态性的β珠蛋白框架 - Suppr

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超能文献

Rapid detection of the highly polymorphic beta globin framework by denaturing gradient gel electrophoresis.

作者信息

Losekoot M, van Heeren H, Schipper J J, Giordano P C, Bernini L F, Fodde R

机构信息

Department of Human Genetics, Leiden University, The Netherlands.

出版信息

J Med Genet. 1992 Aug;29(8):574-7. doi: 10.1136/jmg.29.8.574.

DOI:10.1136/jmg.29.8.574

PMID:1355561

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1016066/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f8b/1016066/be9e81dd31d9/jmedgene00022-0057-a.jpg

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本文引用的文献

Linkage of beta-thalassaemia mutations and beta-globin gene polymorphisms with DNA polymorphisms in human beta-globin gene cluster.人类β-珠蛋白基因簇中β-地中海贫血突变及β-珠蛋白基因多态性与DNA多态性的连锁关系

Nature. 1982 Apr 15;296(5858):627-31. doi: 10.1038/296627a0.

Prenatal diagnosis of beta-thalassemias by amniocentesis: linkage analysis using multiple polymorphic restriction endonuclease sites.通过羊膜穿刺术进行β地中海贫血的产前诊断：利用多个多态性限制性内切酶位点进行连锁分析

Blood. 1980 Nov;56(5):926-30.

Construction of a genetic linkage map in man using restriction fragment length polymorphisms.利用限制性片段长度多态性构建人类遗传连锁图谱。

Am J Hum Genet. 1980 May;32(3):314-31.

DNA polymorphism and molecular pathology of the human globin gene clusters.人类珠蛋白基因簇的DNA多态性与分子病理学

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Detection and localization of single base changes by denaturing gradient gel electrophoresis.通过变性梯度凝胶电泳检测和定位单碱基变化

Methods Enzymol. 1987;155:501-27. doi: 10.1016/0076-6879(87)55033-9.

Resolution of a missense mutant in human genomic DNA by denaturing gradient gel electrophoresis and direct sequencing using in vitro DNA amplification: HPRT Munich.利用变性梯度凝胶电泳和体外DNA扩增直接测序法解析人类基因组DNA中的错义突变体：HPRT慕尼黑突变体

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