Zouros E, Freeman K R, Ball A O, Pogson G H
Department of Biology, Dalhousie University, Halifax, Nova Scotia, Canada.
Nature. 1992 Oct 1;359(6394):412-4. doi: 10.1038/359412a0.
Inheritance of mitochondrial DNA in animals was thought to be strictly maternal. Recently, evidence for incidental paternal mtDNA leakage was obtained in hybrid crosses of Drosophila and mice. In mice, the frequency of paternal mtDNA contributions was estimated at 10(-4), compared with maternal contributions. The common occurrence in the marine mussel Mytilus of heteroplasmic individuals with two or more types of highly diverged mtDNA molecules was interpreted as strong evidence for biparental mtDNA inheritance by some, but not by others. We report here results from pair-matings involving two species of mussels, Mytilus edulis and Mytilus trossulus. Extensive contribution of paternal mtDNA, amounting to several orders of magnitude higher than that inferred for Drosophila or mice, was observed in both intra- and interspecific crosses.
动物中线粒体DNA的遗传曾被认为是严格母系遗传的。最近，在果蝇和小鼠的杂交中获得了父系线粒体DNA偶然泄漏的证据。在小鼠中，与母系遗传相比，父系线粒体DNA的遗传频率估计为10^(-4)。海洋贻贝紫贻贝中存在具有两种或更多种高度分化的线粒体DNA分子的异质个体，这一普遍现象被一些人解释为双亲线粒体DNA遗传的有力证据，但另一些人并不这样认为。我们在此报告了涉及两种贻贝，即紫贻贝和翡翠贻贝的配对交配结果。在种内和种间杂交中均观察到父系线粒体DNA的广泛遗传，其数量比果蝇或小鼠中推断的数量高出几个数量级。
