Yamashita H, Bagger-Sjöbäck D, Sekitani T
Department of Otolaryngology, Yamaguchi University School of Medicine, Ube, Japan.
Auris Nasus Larynx. 1992;19(2):63-8. doi: 10.1016/s0385-8146(12)80093-9.
The distribution of tyrosine hydroxylase (TH)-like immunofluorescence was analyzed in the guinea pig vestibular ganglia and end organs using a monoclonal antibody to TH. TH was chosen as a marker for the sympathetic fibers because TH regulates the first step of catecholamine synthesis by converting tyrosine to dopa. In the vestibular ganglia, there were TH-positive nerve fibers having distinct varicosities surrounding the vestibular ganglion cells. In the sensory areas, there was a sympathetic plexus in the subepithelial tissue of the saccule, the utricle, and the crista ampullaris. We speculated that the sympathetic innervation has a direct influence on the vestibular ganglion cells and diffuse influence on the capillary permeability.
使用抗酪氨酸羟化酶（TH）的单克隆抗体，分析了豚鼠前庭神经节和终器中TH样免疫荧光的分布。选择TH作为交感神经纤维的标志物，因为TH通过将酪氨酸转化为多巴来调节儿茶酚胺合成的第一步。在前庭神经节中，有TH阳性神经纤维围绕前庭神经节细胞，具有明显的膨体。在感觉区域，球囊、椭圆囊和壶腹嵴的上皮下组织中有一个交感神经丛。我们推测交感神经支配对前庭神经节细胞有直接影响，对毛细血管通透性有弥散性影响。
