Van den Brink G, Bollen C W, Van de Wall O E, Hoeve L J, Porsius A J
Department of Pharmacotherapy, University of Utrecht, The Netherlands.
Pharm Weekbl Sci. 1992 Oct 16;14(5):311-5. doi: 10.1007/BF01977619.
This study presents the results of an analysis of the pharmacy records of 778 patients with asthma or chronic obstructive lung diseases. The high percentage of patients taking oral corticosteroids was striking. Inhaled beta-agonists for use as needed have been prescribed to only a minority of patients using these agents. Only half of the patients on beta-agonists used inhaled corticosteroids prophylactically. Drug interactions capable of causing changes in plasma theophylline concentrations appeared in only a small number of patients. The results from studies like the one presented here can provide valuable data to be used for further discussion between physicians and pharmacists about rational drug therapy.
本研究展示了对778例哮喘或慢性阻塞性肺疾病患者的药房记录分析结果。服用口服皮质类固醇的患者比例之高令人瞩目。按需使用的吸入型β受体激动剂仅被开给了少数使用这些药物的患者。使用β受体激动剂的患者中只有一半预防性使用吸入型皮质类固醇。仅少数患者出现了能够引起血浆茶碱浓度变化的药物相互作用。像这里展示的这类研究结果可为医生和药剂师之间关于合理药物治疗的进一步讨论提供有价值的数据。
