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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Hsu J C, Tanaka K, Inayama I, Ohtani S

Department of Animal Science and Technology, Faculty of Agriculture, Gifu University, Japan.

Comp Biochem Physiol Comp Physiol. 1992 Jul;102(3):569-72. doi: 10.1016/0300-9629(92)90211-8.

Isolated hepatocytes from chicks were used to study the effects of pantethine supplementation to incubation medium on in vitro lipogenesis, CO2 production and beta-oxidation of fatty acid. 2. In vitro lipogenesis, determined by the incorporation of 1-[14C]acetate into total lipid and various lipid fractions, as depressed in concordance with the increase of pantethine concentration in the medium. 3. Incubation of isolated hepatocytes with pantethine resulted in a significant decrease (P < 0.01) in the activities of acetyl-CoA carboxylase and fatty acid synthetase. 4. The results suggest that in vitro fatty acid synthesis from 1-[14C]acetate was depressed and CO2 production was elevated in hepatocytes of chicks through pantethine addition to the medium at a low level.

Hsu J C, Tanaka K, Inayama I, Ohtani S

Department of Animal Science and Technology, Faculty of Agriculture, Gifu University, Japan.

Comp Biochem Physiol Comp Physiol. 1992 Jul;102(3):569-72. doi: 10.1016/0300-9629(92)90211-8.

Isolated hepatocytes from chicks were used to study the effects of pantethine supplementation to incubation medium on in vitro lipogenesis, CO2 production and beta-oxidation of fatty acid. 2. In vitro lipogenesis, determined by the incorporation of 1-[14C]acetate into total lipid and various lipid fractions, as depressed in concordance with the increase of pantethine concentration in the medium. 3. Incubation of isolated hepatocytes with pantethine resulted in a significant decrease (P < 0.01) in the activities of acetyl-CoA carboxylase and fatty acid synthetase. 4. The results suggest that in vitro fatty acid synthesis from 1-[14C]acetate was depressed and CO2 production was elevated in hepatocytes of chicks through pantethine addition to the medium at a low level.