人类表皮的电子显微镜研究：马森氏透明细胞（树突状细胞或黑素细胞）。
Electron microscope studies of the human epidermis: the clear cell of Masson (dendritic cell or melanocyte).
作者信息
CLARK W H, HIBBS R G
出版信息
J Biophys Biochem Cytol. 1958 Nov 25;4(6):679-84. doi: 10.1083/jcb.4.6.679.
Abstract
The human epidermis has been studied by electron microscopy following osmium tetroxide and potassium permanganate fixation. An anatomically distinct cell in the human epidermis has been demonstrated with features similar to the melanocyte of the hair bulb described by Barnicot, Birbeck and Cuckow (3). It is dendritic in form and does not contain tonofilaments. "Intercellular bridges" are not formed. The mitochondria are larger and more numerous than those of other epidermal cells and the endoplasmic reticulum is more complex. Some of these cells contain melanin but others are melanin-free. The cell has been interpreted as being identical with the dopa-positive, clear cell of Masson (dendritic cell of Bloch or melanocyte). We have found that many membranous structures in the human epidermis are better preserved by permanganate fixation than by osmium tetroxide fixation.
摘要
在采用四氧化锇和高锰酸钾固定后，通过电子显微镜对人体表皮进行了研究。已证实在人体表皮中存在一种在解剖学上有明显区别的细胞，其特征与巴尼科特、伯贝克和库克奥（3）所描述的毛球黑素细胞相似。它呈树突状，不含张力细丝。不形成“细胞间桥”。其线粒体比其他表皮细胞的更大且数量更多，内质网也更复杂。这些细胞中有些含有黑色素，但有些不含黑色素。该细胞被解释为与马森的多巴阳性透明细胞（布洛赫的树突状细胞或黑素细胞）相同。我们发现，人体表皮中的许多膜性结构用高锰酸钾固定比用四氧化锇固定保存得更好。
相似文献
1
Electron microscope studies of the human epidermis: the clear cell of Masson (dendritic cell or melanocyte).人类表皮的电子显微镜研究：马森氏透明细胞（树突状细胞或黑素细胞）。
J Biophys Biochem Cytol. 1958 Nov 25;4(6):679-84. doi: 10.1083/jcb.4.6.679.
2
Electron microscope observations of the melanocyte of the human epidermis.人表皮黑素细胞的电子显微镜观察
J Biophys Biochem Cytol. 1959 Aug;6(1):41-4. doi: 10.1083/jcb.6.1.41.
3
Electron microscope studies of the human epidermis; the cell boundaries and topography of the stratum malpighii.人类表皮的电子显微镜研究；马尔皮基层的细胞边界和拓扑结构。
J Biophys Biochem Cytol. 1959 Aug;6(1):71-6. doi: 10.1083/jcb.6.1.71.
4
An electron microscope study of the epidermis of mammalian skin in thin sections. I. Dermo-epidermal junction and basal cell layer.哺乳动物皮肤表皮薄切片的电子显微镜研究。I. 真皮-表皮交界处和基底细胞层。
J Biophys Biochem Cytol. 1955 Sep 25;1(5):429-44. doi: 10.1083/jcb.1.5.429.
5
INTRAMITOCHONDRIAL FIBERS WITH DNA CHARACTERISTICS. I. FIXATION AND ELECTRON STAINING REACTIONS.具有DNA特征的线粒体内纤维。I. 固定及电子染色反应
J Cell Biol. 1963 Dec;19(3):593-611. doi: 10.1083/jcb.19.3.593.
6
Electron microscope studies of epidermal melanocytes, and the fine structure of melanin granules.表皮黑素细胞的电子显微镜研究及黑素小体的精细结构。
J Biophys Biochem Cytol. 1960 Sep;8(1):165-80. doi: 10.1083/jcb.8.1.165.
7
The fine structure of the adepidermal reticulum in the basal membrane of the skin of the newt, Triturus.蝾螈（Triturus）皮肤基底膜中表皮下网状组织的精细结构。
J Biophys Biochem Cytol. 1959 Aug;6(1):35-40. doi: 10.1083/jcb.6.1.35.
8
ELECTRON MICROSCOPY OF MELANOCYTES AND MELANOSOMES IN FRECKLED HUMAN EPIDERMIS.雀斑样人类表皮中黑素细胞和黑素体的电子显微镜观察
J Invest Dermatol. 1964 May;42:389-94. doi: 10.1038/jid.1964.84.
9
Fixation of neural tissues for electron microscopy by perfusion with solutions of osmium tetroxide.通过用四氧化锇溶液灌注来固定用于电子显微镜检查的神经组织。
J Cell Biol. 1962 Feb;12(2):385-410. doi: 10.1083/jcb.12.2.385.
引用本文的文献
1
Human nonvisual opsin 3 regulates pigmentation of epidermal melanocytes through functional interaction with melanocortin 1 receptor.人类非视觉 opsin 3 通过与黑素皮质素 1 受体的功能相互作用调节表皮黑素细胞的色素沉着。
Proc Natl Acad Sci U S A. 2019 Jun 4;116(23):11508-11517. doi: 10.1073/pnas.1902825116. Epub 2019 May 16.
2
[Not Available].[无可用内容]
Wilhelm Roux Arch Entwickl Mech Org. 1961 May;153(3):283-313. doi: 10.1007/BF00573436.
3
AN ELECTRON MICROSCOPIC STUDY OF THE HOMOGRAFT REACTION.同种移植反应的电子显微镜研究。
Am J Pathol. 1964 Feb;44(2):319-47.
4
[ON THE HISTOGENESIS OF VERRUCA SEBORRHOICA. II. ELECTRON MICROSCOPE FINDINGS].[关于脂溢性疣的组织发生学。II. 电子显微镜观察结果]
Arch Klin Exp Dermatol. 1963 Dec 10;217:627-51.
5
A STUDY OF THE FINE STRUCTURE OF THE EPIDERMIS OF RANA PIPIENS.牛蛙表皮精细结构的研究。
J Cell Biol. 1964 Jan;20(1):85-94. doi: 10.1083/jcb.20.1.85.
6
The fine structure of normal and neoplastic melanocytes in the Syrian hamster, with particular reference to carcinogen-induced melanotic tumors.叙利亚仓鼠正常和肿瘤性黑素细胞的精细结构，特别涉及致癌物诱导的黑素瘤
J Cell Biol. 1963 Jan;16(1):171-86. doi: 10.1083/jcb.16.1.171.
7
An electron microscope study of the cornea in mice, with special reference to the innervation.小鼠角膜的电子显微镜研究，特别涉及神经支配。
J Anat. 1960 Jul;94(Pt 3):387-409.
8
A comparative micromorphologic study of normal human epidermis and a human squamous cell carcinoma transplant.正常人类表皮与人类鳞状细胞癌移植体的比较微观形态学研究。
Am J Pathol. 1960 Jul;37(1):101-20.
9
10
Electron microscope studies of the human epidermis; the cell boundaries and topography of the stratum malpighii.人类表皮的电子显微镜研究；马尔皮基层的细胞边界和拓扑结构。
J Biophys Biochem Cytol. 1959 Aug;6(1):71-6. doi: 10.1083/jcb.6.1.71.
本文引用的文献
1
Dendritic cells in pigmented human skin.人类色素沉着皮肤中的树突状细胞。
J Anat. 1949 Apr;83(2):109-15.
2
A study of fixation for electron microscopy.电子显微镜固定研究。
J Exp Med. 1952 Mar;95(3):285-98. doi: 10.1084/jem.95.3.285.
3
The keratinization of epidermis and its derivatives, especially the hair, as shown by x-ray diffraction and histochemical studies.如X射线衍射和组织化学研究所示，表皮及其衍生物尤其是毛发的角化过程。
Ann N Y Acad Sci. 1951 Mar;53(3):613-26. doi: 10.1111/j.1749-6632.1951.tb31963.x.
4
The electron microscopy of human hair pigments.人类毛发色素的电子显微镜检查
Ann Hum Genet. 1955 Feb;19(3):231-49. doi: 10.1111/j.1469-1809.1955.tb01346.x.
5
The tonofibrils of the human epidermis.人类表皮的张力原纤维。
J Invest Dermatol. 1957 Nov;29(5):327-38. doi: 10.1038/jid.1957.108.
6
Observations on the fine structure of the turtle atrium.关于龟心房精细结构的观察
J Biophys Biochem Cytol. 1958 Jan 25;4(1):63-72. doi: 10.1083/jcb.4.1.63.
7
An electron microscope study of thin sections of human skin. II. Superficial cell layers of footpad epidermis.人体皮肤薄片的电子显微镜研究。II. 足垫表皮的表层细胞层。
J Invest Dermatol. 1957 Aug;29(2):131-49. doi: 10.1038/jid.1957.80.
8
The electron microscopy of the human hair follicle. I. Introduction and the hair cortex.人类毛囊的电子显微镜检查。I. 引言与毛发皮质
J Biophys Biochem Cytol. 1957 Mar 25;3(2):203-14. doi: 10.1083/jcb.3.2.203.
9
Permanganate; a new fixative for electron microscopy.高锰酸盐；一种用于电子显微镜的新型固定剂。
J Biophys Biochem Cytol. 1956 Nov 25;2(6):799-802. doi: 10.1083/jcb.2.6.799.
10
The structure and formation of pigment granules in human hair.人类头发中色素颗粒的结构与形成
Exp Cell Res. 1956 Apr;10(2):505-14. doi: 10.1016/0014-4827(56)90022-2.
Zotero 插件