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淡水螺类尖膀胱螺(腹足纲,前鳃亚纲)血细胞中免疫反应性脊椎动物生物活性肽物质的存在。

The presence of immunoreactive vertebrate bioactive peptide substances in hemocytes of the freshwater snail Viviparus ater (Gastropoda, Prosobranchia).

作者信息

Ottaviani E, Franchini A, Fontanili P

机构信息

Department of Animal Biology, University of Modena, Italy.

出版信息

Cell Mol Neurobiol. 1992 Oct;12(5):455-62. doi: 10.1007/BF00711546.

Abstract
  1. Using an immunocytochemical procedure a wide range of immunoreactive vertebrate bioactive peptides (BAPs) has been found in hemocytes of Viviparus ater: bombesin, calcitonin, CCK-8, CCK-39, GH, glucagon, insulin, oxytocin, neurotensin, secretin, serotonin, somatostatin, substance P, vasopressin, and VIP. 2. No immunostaining was observed for antigastrin and antithyroglobulin antibodies. 3. The presence of BAP-like molecules in hemocytes suggests a correlation between hemocyte and APUD cells and is evidence of a relationship between the neuroendocrine and the immune systems.
摘要
  1. 采用免疫细胞化学方法,在田螺的血细胞中发现了多种具有免疫反应性的脊椎动物生物活性肽(BAPs):蛙皮素、降钙素、胆囊收缩素-8(CCK-8)、胆囊收缩素-39(CCK-39)、生长激素、胰高血糖素、胰岛素、催产素、神经降压素、促胰液素、5-羟色胺、生长抑素、P物质、血管加压素和血管活性肠肽(VIP)。2. 抗胃泌素和抗甲状腺球蛋白抗体未观察到免疫染色。3. 血细胞中存在BAP样分子表明血细胞与APUD细胞之间存在相关性,并且是神经内分泌系统与免疫系统之间存在关系的证据。

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Neuropeptides: conductors of the immune orchestra.神经肽:免疫乐团的指挥者。
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