Hayata T, Matsu T, Kawano Y, Matsui N, Miyakawa I
Department of Obstetrics and Gynecology, Oita Medical University, Japan.
Int J Gynaecol Obstet. 1992 Dec;39(4):311-9. doi: 10.1016/0020-7292(92)90263-i.
To determine whether the epithelium of an endometriotic lesion has eutopic endometrial glandular epithelium morphology or not for the histogenesis of endometriosis.
Scanning electron microscopy (SEM) of the endometrium was done for 25 cases. Histologically proven endometriotic lesions of 10 of these 25 cases were processed for SEM. Peroneum samples of another 15 cases without histological endometriosis were also studied.
Three of 10 cases with histologically proven endometriotic lesions revealed endometrium-like morphology by SEM, whereas normal appearing peritoneum without histological endometriosis in 15 cases showed no endometrium-like structures by SEM.
Although abovementioned results did not support retrograde menstruation and implantation, they suggested a possibility of derivation from the endometrium.
确定子宫内膜异位症病变的上皮是否具有在位子宫内膜腺上皮形态，以探讨子宫内膜异位症的组织发生。
对25例子宫内膜进行扫描电子显微镜（SEM）检查。这25例中的10例经组织学证实为子宫内膜异位症病变，对其进行SEM处理。另外对15例无组织学子宫内膜异位症的腹膜样本也进行了研究。
10例经组织学证实为子宫内膜异位症病变的病例中，3例通过SEM显示出类似子宫内膜的形态，而15例无组织学子宫内膜异位症的正常外观腹膜在SEM下未显示出类似子宫内膜的结构。
尽管上述结果不支持经血逆流和种植学说，但提示了源自子宫内膜的可能性。
