Willgeroth C, Floegel R, Rösler B
Institut für Pathologie, Medizinischen Akademie Magdeburg.
Zentralbl Chir. 1992;117(11):603-6.
In a period of 10 years (1981-90) papillary thyroid carcinomas were found in 124 cases. In 95 cases we were able to perform immunohistochemical studies for Leu-M1 antigen and S-100 protein. The examination of these cases has revealed that the presence of S-100 positive Langerhans cells yields no additional information for the prognosis of the papillary thyroid carcinoma. But we observed that the existence of Leu-M1 positive tumour cells is connected with a poor postoperative course of disease in comparison to Leu-M1 negative tumours.
在10年期间（1981 - 1990年），共发现124例甲状腺乳头状癌。其中95例能够进行针对Leu - M1抗原和S - 100蛋白的免疫组织化学研究。对这些病例的检查显示，S - 100阳性朗格汉斯细胞的存在对于甲状腺乳头状癌的预后并无额外信息。但我们观察到，与Leu - M1阴性肿瘤相比，Leu - M1阳性肿瘤细胞的存在与术后疾病进程不佳有关。
