Durand P Y, Chanliau J, Gamberoni J, Hestin D, Kessler M
ALTIR & Nephrology Department, Chru Nancy, France.
Adv Perit Dial. 1992;8:22-5.
Peritoneal permeability (PP), hydrostatic intraperitoneal pressure (IPP) and the overall volume of ultrafiltration (UF) were measured in 23 patients treated by CAPD under stable conditions. PP, IPP and UF were measured during the same exchange with a 2-liter bag with 3.86% glucose, dwell time of 2 hours. PP was evaluated with 3 indices: glucose peritoneal desaturation at 2 hours, urea peritoneal saturation at 2 hours, and crossing time of glucose and urea peritoneal equilibration curves. IPP was evaluated at inspiration (IPPinsp) and at expiration (IPPexp)-giving IPPmean-by measuring the height of the dialysis fluid in the PD line under atmospheric pressure, with point zero located on the axillary line of the subject in strict supine position. Net UF volume was inversely correlated with IPPmean. The net UF volume was strongly affected by IPP since a 1 cmH2O increase in IPPmean caused a decrease of 74 ml in global UF in 2 hours, probably by modification of the lymphatic reabsorption and perhaps of the transcapillary UF.
在稳定条件下，对23例接受持续性非卧床腹膜透析（CAPD）治疗的患者测量了腹膜通透性（PP）、腹腔内静水压（IPP）和超滤总量（UF）。在使用2升含3.86%葡萄糖的袋子进行相同交换且留腹时间为2小时的过程中，测量PP、IPP和UF。PP通过3个指标进行评估：2小时时葡萄糖腹膜去饱和、2小时时尿素腹膜饱和以及葡萄糖和尿素腹膜平衡曲线的交叉时间。通过在大气压下测量腹膜透析管中透析液的高度来评估吸气时（IPPinsp）和呼气时（IPPexp）的IPP，从而得出IPPmean，零点位于受试者严格仰卧位时的腋线上。净超滤量与IPPmean呈负相关。净超滤量受IPP的强烈影响，因为IPPmean每增加1 cmH2O，2小时内总超滤量就会减少74 ml，这可能是由于淋巴重吸收的改变以及或许还有跨毛细血管超滤的改变所致。
