Clewell W, Meschia G
Am J Obstet Gynecol. 1976 Jun 15;125(4):507-8. doi: 10.1016/0002-9378(76)90366-5.
Measurable reduction of the metabolic clearance rate of DS does not reflect alterations of placental blood flow. The fact that large changes in the MCR are observed in complicated pregnancies implies a metabolic change in the placenta.