子宫胎盘血流与母体血浆C-19类固醇胎盘清除率的关系：数学模型评估
Relationship of uteroplacental blood flow to placental clearance of maternal plasma C-19 steroids: evaluation of mathematical models.
作者信息
Senner J W, Stanczyk F Z, Fritz M A, Novy M J
出版信息
Am J Obstet Gynecol. 1985 Nov 1;153(5):573-5. doi: 10.1016/0002-9378(85)90481-8.
The concept that the placental clearance of maternal plasma dehydroepiandrosterone sulfate through estradiol formation is a function of uteroplacental blood flow in women has been disputed. We obtained data on the clearance of maternal plasma dehydroepiandrosterone through placental estradiol formation in the baboon and used these data to evaluate some mathematical models of placental clearance. Our evaluation shows that the placental clearance of dehydroepiandrosterone is proportional to uteroplacental blood flow in the baboon.
母体血浆硫酸脱氢表雄酮通过雌二醇形成的胎盘清除率是女性子宫胎盘血流量的函数这一概念一直存在争议。我们获得了狒狒母体血浆脱氢表雄酮通过胎盘雌二醇形成的清除率数据，并利用这些数据评估了一些胎盘清除的数学模型。我们的评估表明，狒狒中脱氢表雄酮的胎盘清除率与子宫胎盘血流量成正比。
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