Rameis H
Arbeitsgruppe für angewandte klinische Pharmakologie, Wien.
Wien Med Wochenschr. 1992;142(18):398-405.
In the light of recent findings the therapeutic importance of various H2-blockers (e.g. cimetidine, ranitidine, famotidine) in short-term and long-term treatment of peptic ulcers is discussed. Special interest is paid to the clinical pharmacology (pharmacokinetics, pharmacodynamics) and undesired effects of the compounds. New aspects in the pathogenesis of peptic ulcer disease were considered, with regard to the pharmacologic profile of H2-blocker.
根据最近的研究结果，讨论了各种H2受体阻滞剂（如西咪替丁、雷尼替丁、法莫替丁）在消化性溃疡短期和长期治疗中的治疗重要性。特别关注这些化合物的临床药理学（药代动力学、药效学）和不良反应。结合H2受体阻滞剂的药理学特征，考虑了消化性溃疡疾病发病机制的新方面。
