ADELMAN W J, ADAMS J
J Gen Physiol. 1959 Jan 20;42(3):655-64. doi: 10.1085/jgp.42.3.655.
The effects of external calcium deprivation on certain characteristics of the action potential of the lobster motor axon have been studied. Upon exposure to calcium-free solution the spike amplitude is rapidly decreased within a few minutes and is followed by a slow linear decline. The rates of spike rise and fall are proportionally reduced more than the spike but follow similar time courses during calcium lack. Associated with these phenomena are the loss in the normal slow spike repolarization process, the development of a large and lengthy undershoot, and the appearance of a high degree of refractoriness. The mean increase in the refractory period is 525 per cent upon 10 minutes' exposure to calcium-free solution. These effects are completely reversible upon returning the axons to normal solution. These results are compared to similar effects of calcium deprivation on frog myelinated axons and squid and lobster giant axons recently observed by other workers.
研究了外部钙缺失对龙虾运动轴突动作电位某些特性的影响。暴露于无钙溶液后，峰电位幅度在几分钟内迅速下降，随后缓慢线性下降。峰电位上升和下降的速率比峰电位成比例地降低更多，但在缺钙期间遵循相似的时间进程。与这些现象相关的是正常的缓慢峰电位复极化过程的丧失、大且长的负后电位的出现以及高度不应期的出现。暴露于无钙溶液10分钟后，不应期平均增加525%。将轴突恢复到正常溶液后，这些效应是完全可逆的。将这些结果与其他研究人员最近观察到的钙缺失对青蛙有髓轴突、鱿鱼和龙虾巨轴突的类似影响进行了比较。
