Venters M, Schacht L, Bensel R T
Am J Public Health. 1976 Nov;66(11):1099-100. doi: 10.2105/ajph.66.11.1099.
Following a study of 421 suspected cases of Down's syndrome which were referred during a 10-year period to the Human Genetics Unit of the Minnesota Department of Health for chromosomal analysis, the following conclusions were reached: 1. There was an overall underreporting on the matched birth certificate of 52% of the cytogenetically confirmed cases. 2. This underreporting on birth certificates was greater (79%) for those born in the years 1946-1964 when less specific information was requested than in more recent years (36%), 1967-1974, when identification of the abnormality was requested.
在对421例疑似唐氏综合征病例进行研究后得出以下结论：这些病例在10年期间被转介至明尼苏达州卫生部人类遗传学部门进行染色体分析。1. 在匹配的出生证明上，细胞遗传学确诊病例的总体漏报率为52%。2. 出生证明上的这种漏报情况在1946年至1964年出生的人群中更为严重（79%），当时所要求提供的信息不如近年来（1967年至1974年）具体，近年来要求对异常情况进行识别。
