Frantsuzova S B, Arshinnikova L L, Antonenko L I, Iatsenko V P
Biull Eksp Biol Med. 1992 Sep;114(9):244-6.
The influence of alpha-adrenoblocking drug tropaphen on cardio- and haemodynamics under experimental lung-heart failure was studied in dogs. The findings suggest effectiveness of tropaphen administration in such pathology shown by a decrease of lung hypertension and heart overload, significant increase of the contractile activity and relaxation properties of myocardium of both ventricles and in cardiac pump function optimization.
研究了α-肾上腺素能阻断药托拉酚在实验性肺心病心力衰竭状态下对心脏和血液动力学的影响。研究结果表明,托拉酚在此类病理状态下具有有效性,表现为肺动脉高压和心脏负荷降低、双心室心肌收缩活性和舒张特性显著增加以及心脏泵功能优化。