Said J W
Department of Pathology, Cedars Sinai Medical Center, Los Angeles, CA 90048.
Semin Diagn Pathol. 1992 Nov;9(4):265-71.
Immunohistochemistry is a valuable adjunct to the identification of Hodgkin's disease (HD) Reed-Sternberg (RS) cells, and in the differential diagnosis between HD, non-Hodgkin's lymphomas, and nonlymphoid neoplasms containing RS-like cells. The characteristic phenotype of RS cells in different subtypes of HD is described, with an emphasis on routine immunohistochemical stains. Some of the conflicting literature on this subject is reviewed to highlight pitfalls and controversies in the field.
免疫组织化学是鉴定霍奇金病（HD）里德-斯腾伯格（RS）细胞的一项重要辅助手段，对于HD、非霍奇金淋巴瘤以及含有RS样细胞的非淋巴样肿瘤的鉴别诊断也很有价值。本文描述了HD不同亚型中RS细胞的特征性表型，重点介绍常规免疫组织化学染色。回顾了关于该主题的一些存在争议的文献，以突出该领域的陷阱和争议。
