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一种用于解释犯罪案件中DNA单基因座分析数据的有效统计程序。

An efficient statistical procedure for interpreting DNA single locus profiling data in crime cases.

作者信息

Evett I W, Scranage J K, Pinchin R

机构信息

Central Research and Support Establishment, Forensic Science Service, Reading, Berkshire, United Kingdom.

出版信息

J Forensic Sci Soc. 1992 Oct-Dec;32(4):307-26. doi: 10.1016/s0015-7368(92)73088-6.

Abstract

This paper describes a simplified approach to calculating the Bayesian likelihood ratio for the case where two DNA single locus profiles are to be compared. It explains how the calculation allows for band shift and also for the variation in precision with molecular weight. A simple basic theory section explains the principles of the analysis but more detailed explanations are given in an advanced theory section. Experiments on substantial data collections are described which demonstrate the robustness of the method.

摘要

本文描述了一种用于比较两个DNA单基因座图谱情况的贝叶斯似然比的简化计算方法。它解释了该计算如何考虑条带移动以及分子量精度的变化。一个简单的基础理论部分解释了分析原理,但在高级理论部分给出了更详细的解释。文中描述了对大量数据集合进行的实验,这些实验证明了该方法的稳健性。

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