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[出生后早期心肌糖酵解活性受抑制的机制]

[Mechanism of inhibition of the glycolytic activity of the myocardium during the early postnatal period].

作者信息

Larionov N P

出版信息

Biull Eksp Biol Med. 1976 Sep;82(9):1054-5.

PMID:136280
Abstract

Reduction of the activity of glycolysis and glycogenolysis regularly observed in the developing cardiac muscle was not associated with reduction of the glycolytic system, but was due to the regulatory inhibition of the phosphofructokinase link in the glycolytic link. This was indicated by a 4.5-fold increase in the rat heart of the ratio of the active masses of the phosphofructokinase reaction in the course of 2 weeks of the postnatal development.

摘要

在发育中的心肌中经常观察到的糖酵解和糖原分解活性降低,与糖酵解系统的减少无关,而是由于糖酵解途径中磷酸果糖激酶环节的调节性抑制。这一点通过出生后2周内大鼠心脏中磷酸果糖激酶反应活性物质的比例增加了4.5倍得到了证明。

相似文献

1
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Biull Eksp Biol Med. 1976 Sep;82(9):1054-5.
2
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