Petersen C S, Menné T
Department of Dermatology, Gentofte Hospital, Copenhagen, Denmark.
Acta Derm Venereol. 1992 Nov;72(6):436-7.
A patient with an otherwise recalcitrant chronic vesicular hand eczema responded with a dramatical improvement within 2 weeks of cyclosporin A (CsA) therapy 5.0 mg/kg daily. The patient was still free of eczema in spite of reducing the CsA dose to 2.5 mg/kg daily. CsA therapy was finally stopped due to a moderate increase in blood pressure, resulting in rapid recurrence of the hand eczema. The case report clearly demonstrates that oral CsA should be considered in patients with severe hand eczema that cannot be controlled on conventional immunosuppressive treatments.
一名患有顽固性慢性水疱性手部湿疹的患者，在每天服用5.0毫克/千克环孢素A（CsA）治疗的2周内病情显著改善。尽管将CsA剂量减至每天2.5毫克/千克，该患者仍未出现湿疹。最终因血压适度升高而停止CsA治疗，结果手部湿疹迅速复发。该病例报告清楚地表明，对于常规免疫抑制治疗无法控制的严重手部湿疹患者，应考虑使用口服CsA。
