FINE M
Calif Med. 1959 Feb;90(2):121-5.
At present, corneal transplantation is the only definitive means of controlling or terminating recurrent or chronic herpetic keratitis. Of 48 keratoplastic operations for various forms of corneal herpes, 16 in quiescent cases and 32 in cases of active keratitis, all but three brought about improvement. Recurrence of keratitis in the graft is particularly likely if the visible lesion is not excised completely and a portion of the graft border lies in contact with diseased tissue. The mode of action of corneal transplantation in improving herpetic keratitis is not clear but several possibilities have been suggested. At least in chronic stromal herpes the removal of diseased and necrotic tissue appears to be a very important factor.
目前,角膜移植是控制或终止复发性或慢性疱疹性角膜炎的唯一确定性手段。在48例针对各种形式角膜疱疹的角膜移植手术中,16例为静止期病例,32例为活动性角膜炎病例,除3例之外其余均有改善。如果可见病变未完全切除且移植片边缘的一部分与患病组织接触,则移植片中的角膜炎特别容易复发。角膜移植改善疱疹性角膜炎的作用方式尚不清楚,但已提出了几种可能性。至少在慢性基质性疱疹中,去除患病和坏死组织似乎是一个非常重要的因素。