Huang C H, Chen L, Hsieh H H
Department of Internal Medicine, Chang Gung Memorial Hospital, Kao-Hsiung, Taiwan R.O.C.
J Formos Med Assoc. 1992 Sep;91(9):922-5.
Choriocarcinoma of the kidney, either primary or metastatic, is rarely reported in the literature. We encountered a male patient with choriocarcinoma of the right kidney. The patient initially presented with fever, gross hematuria and flank pain. He had initially been unsuccessfully treated for bilateral renal stones for four months before an accurate diagnosis was made. The disease was verified only after a resection of the right kidney and meticulous examination of microscopic sections of the tumor. Further immunohistochemical study strongly supported the diagnosis of choriocarcinoma. The tumor responded briefly to Cisplatinum, Vinblastine and Bleomycin (PVB) treatment. The patient died of brain metastasis and respiratory failure four months after starting systemic chemotherapy.
原发性或转移性肾绒毛膜癌在文献中鲜有报道。我们遇到一名右肾绒毛膜癌男性患者。该患者最初表现为发热、肉眼血尿和侧腹痛。在确诊前，他最初因双侧肾结石接受了四个月的治疗，但未成功。仅在切除右肾并对肿瘤组织切片进行细致检查后才确诊该病。进一步的免疫组化研究有力地支持了绒毛膜癌的诊断。肿瘤对顺铂、长春碱和博来霉素（PVB）治疗有短暂反应。患者在开始全身化疗四个月后死于脑转移和呼吸衰竭。
