LEVY B M
Science. 1959 Mar 13;129(3350):720. doi: 10.1126/science.129.3350.720.
Salamander and toad embryos will develop grossly observable tumors of the notochord if they are placed for 3 or more days in a solution of the lathyrism-producing chemicals beta-aminopropionitrile or aminoacetonitrile. A technique for using tumorigenesis in amphibian embryos as a biological indicator for other lathyrogenic agents is presented.