Isnetsov V V
Aviakosm Ekolog Med. 1992 May-Jun;26(3):10-8.
The review contains the present-day evidence on neurophysiological and neurochemical mechanisms of functioning the central components of vomiting reflex. The main attention is concentrated on the role of some brain structures in motion sickness-induced vomiting. At the same time, the literature data casting doubt on traditional view of a necessary involvement of some brain structures in the genesis of vomiting induced by motion sickness are discussed. Also there are findings of studying an effect of physiologically active substances (classical neuromediators and regulatory peptides) at a neuronal level (silent postremal cells) with the presence of an emetic effect in them during systemic administration. The current concept of vomiting center to which role the parvicellular reticular formation of brain stem can pretend is under study.
该综述包含了目前关于呕吐反射中枢成分功能的神经生理和神经化学机制的证据。主要关注点集中在一些脑结构在晕动病诱发呕吐中的作用。同时，也讨论了对某些脑结构在晕动病诱发呕吐的发生中必然参与这一传统观点提出质疑的文献数据。此外，还介绍了在全身给药期间，研究生理活性物质（经典神经递质和调节肽）在神经元水平（延髓后区沉默细胞）产生催吐作用的研究结果。目前正在研究脑干小细胞网状结构可能发挥作用的呕吐中枢的概念。
