Zhou D, Yang Y, Li L, Yuan G, Chen H
Hua Xi Yi Ke Da Xue Xue Bao. 1992 Sep;23(3):241-4.
Using Low shear 30 rheometer, we measured the thixotropic parameters of blood from 30 patients suffering from cerebral thrombosis. The result showed that the yield stress (tau 0), non-Newtonian contribution of viscosity (eta s-mu) and viscosity of plasma (eta p) were significantly higher than those in the control group. Those patients were randomly divided into two groups. Each group included 15 patients. The patients in group 1 and group 2 were treated with poly-saccharide sulphate (PSS) and DX40 respectively by intravenous drip for 14 days. The results showed that tau 0, A, (eta s-mu) were significant decreased in group 1 after treatment, but no significantly change in the thixotropic parameters was found in group 2 after treatment. The total curative rate in group 1 was higher than that in group 2. These results suggest that the patients with cerebral thrombosis had evidently increased degree of RBC aggregation. PSS could decrease the aggregation of RBC more significantly than DX40 did. It was probably one of the reasons why the therapeutic effect of PSS on cerebral thrombosis was better than that of DX40.
使用低切变率30流变仪，我们测量了30例脑血栓患者血液的触变参数。结果显示，屈服应力（τ0）、粘度的非牛顿贡献（ηs-μ）和血浆粘度（ηp）显著高于对照组。这些患者被随机分为两组。每组包括15例患者。第1组和第2组患者分别用硫酸多糖（PSS）和DX40静脉滴注治疗14天。结果显示，治疗后第1组的τ0、A、（ηs-μ）显著降低，但治疗后第2组的触变参数无显著变化。第1组的总治愈率高于第2组。这些结果表明，脑血栓患者红细胞聚集程度明显增加。PSS比DX40更能显著降低红细胞聚集。这可能是PSS对脑血栓的治疗效果优于DX40的原因之一。
