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[铅和锰暴露人群的毒代动力学和毒效动力学指标]

[Toxicokinetic and toxicodynamic indices in persons exposed to lead and manganese].

作者信息

Khadzhieva I

出版信息

Probl Khig. 1992;17:208-12.

PMID:1364543
Abstract

Subject to examination are 161 workers (118 men and 43 women) in professional contact with manganese and lead of the agglomeration production of Kremikovtsi. A complex of toxicokinetic (content of manganese in blood, urine and hair) and toxicodynamic indices is applied. Increased levels of manganese are established in the examined biological media. No plumbemia above 2.88 mumol/l is registered. The excretion of 5-amino-levulinic acid in urine is increased at a low rate. There are no considerable deviations in the clinic and chemical indices.

摘要

接受检查的是克雷米科夫齐烧结厂161名与锰和铅有职业接触的工人(118名男性和43名女性)。应用了一组毒代动力学指标(血液、尿液和头发中的锰含量)和毒效动力学指标。在所检查的生物介质中发现锰水平升高。未检测到血铅水平高于2.88微摩尔/升。尿液中5-氨基-γ-酮戊酸的排泄略有增加。临床和化学指标没有明显偏差。

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