Stoica E, Marinescu D
Morphol Embryol (Bucur). 1976 Oct-Dec;22(4):281-7.
Some cytochemical reactions were performed in order to complete the diagnosis possibilities of pleural effusions from patients with neoplasia and with other diseases. Qualitative reactions were performed on the smears for alkaline phosphatase (samples from 46 patients) for nonspecific esterases (samples from 30 patients), for acid and neutral mucopolysaccharides (samples from 35 patients) and for nucleic acids (samples from 85 patients). On the presented material the presence of alkaline phosphatase could be considered as a malignancy criterium. The activity of nonspecific esterases in the overwhelming majority of the cases cannot represent an aid in distinguishing neoplastic cells. Acid and neutral mucopolysaccarides do not generally constitute a neoplastic criterium, but a helping element in the diagnosis of some mesotheliomas. The evidencing of nucleic acids is very important for the demonstration of nucleoli which are considered as a principal criterium in malignancy.
为了完善对肿瘤患者及其他疾病患者胸腔积液的诊断方法，进行了一些细胞化学反应。对46例患者样本涂片进行了碱性磷酸酶定性反应、对30例患者样本涂片进行了非特异性酯酶定性反应、对35例患者样本涂片进行了酸性和中性粘多糖定性反应以及对85例患者样本涂片进行了核酸定性反应。在所提供的材料上，碱性磷酸酶的存在可被视为恶性肿瘤的一个标准。在绝大多数病例中，非特异性酯酶的活性无助于区分肿瘤细胞。酸性和中性粘多糖一般不构成肿瘤的标准，但在某些间皮瘤的诊断中是一个辅助因素。核酸的检测对于核仁的显示非常重要，而核仁被视为恶性肿瘤的主要标准。
