Vlak T, Jajić I
Klinika za fizikalnu medicinu, rehabilitaciju i reumatologiju Medicinskog fakulteta u KB Sestre milosrdnice, Zagreb.
Reumatizam. 1992;39(1):27-31.
The objective of this research has been to evaluate the efficacy of Tauredon (the aqueous solution of Na-thiomalate) on the development of some clinical parameters in patients with rheumatoid arthritis. The group being tested comprised 8 men and 35 women, their average age being 50, the average duration of their illness being 9.5 years. As regards the anatomic development stage of illness, the majority of patients belonged to stage 2 (62.8%), with no patients belonging to stage 4. During the continuous six-month application of Tauredon, the following parameters have been observed: the Ritchie index, the PIP extent of the fist joints and the morning stiffness span of the small fist joints. The evaluation of the six-month treatment with Tauredon has proved its positive effect on all clinical parameters, shown in the lower value of the Ritchie index, the lower PIP extent of the fist joints as well as the shorter morning stiffness span. Further, the Tauredon effect has been seen in suppressing the inflammatory activities and in restituting the joint functions in patients with rheumatoid arthritis.
本研究的目的是评估硫代苹果酸钠水溶液（Tauredon）对类风湿性关节炎患者某些临床参数发展的疗效。受试组包括8名男性和35名女性，他们的平均年龄为50岁，平均病程为9.5年。就疾病的解剖发展阶段而言，大多数患者属于2期（62.8%），没有患者属于4期。在连续六个月应用Tauredon期间，观察了以下参数：里奇指数、掌指关节的近端指间关节（PIP）范围以及小掌指关节的晨僵时长。对Tauredon进行的为期六个月的治疗评估证明，其对所有临床参数均有积极作用，表现为里奇指数值降低、掌指关节的近端指间关节范围减小以及晨僵时长缩短。此外，在类风湿性关节炎患者中还观察到Tauredon具有抑制炎症活动和恢复关节功能的作用。
