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运动神经元胞体的电压钳制

Voltage clamp of motoneuron soma.

作者信息

FRANK K, FUORTES M G, NELSON P G

出版信息

Science. 1959 Jul 3;130(3366):38-9. doi: 10.1126/science.130.3366.38.

Abstract

Concentric microelectrodes were used to voltage-clamp spinal motoneurons. With depolarizing voltage steps, current transients often appear, with some latency and in all-or-none fashion. Voltage-current relations indicate a two- to threefold reduction in resistance between inside and outside when the cell fires. These results suggest that activity does not involve the whole soma-dendritic membrane.

摘要

采用同心微电极对脊髓运动神经元进行电压钳制。在去极化电压阶跃时,电流瞬变经常出现,有一定潜伏期且呈全或无的形式。电压-电流关系表明,细胞放电时,细胞内外电阻降低两到三倍。这些结果表明,活动并不涉及整个胞体-树突膜。

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