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Combined drug treatment of tuberculosis. I. Prevention of emergence of mutant populations of tubercle bacilli resistant to both streptomycin and isoniazid in vitro.

作者信息

COHN M L, MIDDLEBROOK G, RUSSELL W F

出版信息

J Clin Invest. 1959 Aug;38(8):1349-55. doi: 10.1172/JCI103910.

DOI:10.1172/JCI103910
PMID:13673091
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC442089/
Abstract
摘要

相似文献

1
Combined drug treatment of tuberculosis. I. Prevention of emergence of mutant populations of tubercle bacilli resistant to both streptomycin and isoniazid in vitro.结核病的联合药物治疗。一、体外预防结核杆菌对链霉素和异烟肼均耐药的突变菌群的出现。
J Clin Invest. 1959 Aug;38(8):1349-55. doi: 10.1172/JCI103910.
2
Synergistic effects of antituberculous agents on streptomycin resistant tubercle bacilli. I. In vitro synergistic effects of antituberculous agents on the growth of tubercle bacilli with different degrees of resistance to streptomycin.抗结核药物对链霉素耐药结核杆菌的协同作用。I. 抗结核药物对不同程度链霉素耐药结核杆菌生长的体外协同作用。
Kekkaku. 1954 Feb;29(2):47-54.
3
[Studies on the emergence of resistance of tubercle bacilli to 4-chloroanilide of 5-chlorosalicylic cid in vitro].[结核杆菌对5-氯水杨酸的4-氯苯胺体外耐药性出现的研究]
Gruzlica. 1967 Dec;35(12):1279-84.
4
Biphasic kill curve of isoniazid reveals the presence of drug-tolerant, not drug-resistant, Mycobacterium tuberculosis in the guinea pig.异烟肼的双相杀菌曲线揭示了豚鼠体内存在耐受药物而非耐药的结核分枝杆菌。
J Infect Dis. 2009 Oct 1;200(7):1136-43. doi: 10.1086/605605.
5
[Drug resistance of tubercle bacilli in experimental animals treated with streptomycin and isoniazid].[用链霉素和异烟肼治疗的实验动物中结核杆菌的耐药性]
Kekkaku. 1955 Mar;30(3):114-8; English summary, 154-5.
6
[Analysis of the virulence of tubercle bacilli by selection of streptomycin-resistant mutant].[通过链霉素抗性突变体的筛选分析结核杆菌的毒力]
Kekkaku. 1954 Oct;29(10):383-7; English summary, 416-7.
7
[Fluctuation in the resistance of various populations of human type tubercle bacillus mixed artificially with sensitive bacilli and resistant variants to isoniazid].[人工混合敏感菌和对异烟肼耐药变异株的各人群人型结核杆菌耐药性的波动情况]
Kekkaku. 1955 Mar;30(3):119-22; English summary, 155.
8
[Synergistic effects of antituberculous agents on streptomycin resistant tubercle bacilli. 2. Synergistic effects in vivo of SM and other drugs on the SM (10r/cc) resistant tubercle bacilli].抗结核药物对链霉素耐药结核杆菌的协同作用。2. 链霉素（10r/cc）耐药结核杆菌在体内链霉素与其他药物的协同作用
Kekkaku. 1955 Feb;30(2):72-80; English summary, 100.
9
[Resistance of tubercle bacilli to streptomycin, PAS & isoniazid].结核杆菌对链霉素、对氨基水杨酸及异烟肼的耐药性
Ned Tijdschr Geneeskd. 1958 Nov 22;102(47):2314-8.
10
[Comparative resistance determination of the tubercle bacillus to streptomycin, isoniazid (INH) and to a mixture of streptomycin and isoniazid, in vitro].[结核杆菌对链霉素、异烟肼（INH）以及链霉素与异烟肼混合物的体外耐药性比较测定]
Helv Paediatr Acta. 1953 Dec;8(6):561-6.

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Newer research transforming 24-month treatment of MDR/XDR-TB TO 6 months.最新研究将耐多药/广泛耐药结核病的24个月治疗转变为6个月治疗。
Lung India. 2025 Mar 1;42(2):140-146. doi: 10.4103/lungindia.lungindia_431_24. Epub 2025 Feb 27.
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Drug Resistance in in the Context of Zero Leprosy.零麻风背景下的耐药性
Indian Dermatol Online J. 2021 Nov 22;12(6):791-795. doi: 10.4103/idoj.idoj_599_21. eCollection 2021 Nov-Dec.
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Profound depletion of HIV-1 transcription in patients initiating antiretroviral therapy during acute infection.急性感染期开始抗逆转录病毒治疗的患者中 HIV-1 转录的深度耗竭。
PLoS One. 2010 Oct 12;5(10):e13310. doi: 10.1371/journal.pone.0013310.
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Minority variants of drug-resistant HIV.耐药性 HIV 的少数变体。
J Infect Dis. 2010 Sep 1;202(5):657-66. doi: 10.1086/655397.
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Some Thoughts on the Antibiotic Therapy of Orthopædic Tuberculosis [Summary].关于骨科结核病抗生素治疗的一些思考[摘要]
Proc R Soc Med. 1960 Jun;53(6):442. doi: 10.1177/003591576005300616.
6
The virulence in the guinea-pig of tubercle bacilli isolated before treatment from South Indian patients with pulmonary tuberculosis. I. Homogeneity of the investigation and a critique of the virulence test.对来自南印度肺结核患者治疗前分离出的结核杆菌在豚鼠体内的毒力研究。I. 研究的同质性及毒力测试的评论
Bull World Health Organ. 1961;25(3):285-312.
7
A VERTICAL DIFFUSION METHOD FOR THE MICROBIOLOGICAL ASSAY OF ISONIAZID.异烟肼微生物测定的垂直扩散法
J Clin Pathol. 1964 Nov;17(6):622-6. doi: 10.1136/jcp.17.6.622.
8
Identification of tubercle bacilli from Indian patients with pulmonary tuberculosis.从印度肺结核患者中鉴定结核杆菌。
Bull World Health Organ. 1961;25(6):747-58.
9
Rate of inactivation of isoniazid in South Indian patients with pulmonary tuberculosis.南印度肺结核患者中异烟肼的失活率
Bull World Health Organ. 1961;25(6):765-77.
10
The virulence in the guinea-pig of tubercle bacilli isolated before treatment from South Indian patients with pulmonary tuberculosis. 2. Comparison with virulence of tubercle bacilli from British patients.1. 对来自南印度肺结核患者治疗前分离出的结核杆菌在豚鼠体内的毒力研究。2. 与来自英国患者的结核杆菌毒力的比较。
Bull World Health Organ. 1961;25(3):313-22.

本文引用的文献

1
Origin of Bacterial Resistance to Antibiotics.细菌对抗生素耐药性的起源
J Bacteriol. 1948 Jul;56(1):63-74. doi: 10.1128/jb.56.1.63-74.1948.
2
Sterilization of tubercle bacilli by isonicotinic acid hydrazide and the incidence of variants resistant to the drug in vitro.异烟肼对结核杆菌的杀菌作用及体外对该药耐药变异株的发生率
Am Rev Tuberc. 1952 Jun;65(6):765-7.
3
Studies on the stability of isoniazid.
Am Rev Tuberc. 1955 May;71(5):732-42. doi: 10.1164/artpd.1955.71.5.732.
4
Studies on isoniazid and tubercle bacilli. III. The isolation, drug-susceptibility, and catalase-testing of tubercle bacilli from isoniazid-treated patients.异烟肼与结核杆菌的研究。III. 来自接受异烟肼治疗患者的结核杆菌的分离、药敏性及过氧化氢酶检测
Am Rev Tuberc. 1954 Nov;70(5):852-72. doi: 10.1164/art.1954.70.5.852.
5
Studies on isoniazid and tubercle bacilli. II. The growth requirements, catalase activities, and pathogenic properties of isoniazid-resistant mutants.异烟肼与结核杆菌的研究。II. 异烟肼耐药突变体的生长需求、过氧化氢酶活性及致病特性
Am Rev Tuberc. 1954 Oct;70(4):641-64. doi: 10.1164/art.1954.70.4.641.
6
United States Public Health service cooperative investigation of antimicrobial therapy of tuberculosis, V. Report on thirty-two-week observations on combinations of isoniazid, streptomycin, and para-aminosalicylic acid.美国公共卫生服务局结核病抗菌治疗合作调查，第五部分。关于异烟肼、链霉素和对氨基水杨酸联合使用32周观察结果的报告。
Am Rev Tuberc. 1954 Sep;70(3):521-6. doi: 10.1164/art.1954.70.3.521.
7
Studies on isoniazid and tubercle bacilli. I. The isolation of isoniazid-resistant mutants in vitro.异烟肼与结核杆菌的研究。I. 体外异烟肼耐药突变体的分离
Am Rev Tuberc. 1954 Sep;70(3):465-75. doi: 10.1164/art.1954.70.3.465.
8
Bactericidal activity of streptomycin and isoniazid against tubercle bacilli.链霉素和异烟肼对结核杆菌的杀菌活性。
Br Med J. 1954 Jan 16;1(4854):130-2. doi: 10.1136/bmj.1.4854.130.
9
Control study of comparative efficacy of isoniazid, streptomycin-isoniazid, and streptomycin; para-aminosalicylic acid in pulmonary tuberculosis therapy. IV. Report on forty-week observations on 583 patients with streptomycin susceptible infections.
Am Rev Tuberc. 1953 Aug;68(2):264-9. doi: 10.1164/art.1953.68.2.264.