Stürchler D, Degrémont A
Schweiz Med Wochenschr. 1976 May 15;106(20):682-8.
A discussion is presented on the epidemiological and clinical aspects of filariasis in persons returning from tropical countries. In our population filariasis is mainly imported from central and western Africa, especially Cameroon. Missionaries and voluntary workers spending periods of years in the tropics are particularly exposed. About 50% of the patients are normal on clinical examination and 40% do not even evidence symptoms due to the low parasite density. Therefore, demonstration of the parasite, which is the diagnostic aim, is often very difficult and requires special techniques. Whenever parasite demonstration is impossible, itching, eosinophilia and a positive immunofluorescence reaction are important diagnostic signs, but they may occasionally develop years after the subject's return. Treatment is by diethylcarbamazine and suramine; their administration and side effects are described and 2 cases involving severe reactions due to inadequate treatment are cited.
本文讨论了从热带国家归来人员中丝虫病的流行病学和临床情况。在我们的人群中，丝虫病主要从非洲中部和西部输入，尤其是喀麦隆。在热带地区长期停留的传教士和志愿工作者特别容易感染。约50%的患者临床检查正常，40%甚至因寄生虫密度低而无明显症状。因此，作为诊断目标的寄生虫检测往往非常困难，需要特殊技术。当无法检测到寄生虫时，瘙痒、嗜酸性粒细胞增多和阳性免疫荧光反应是重要的诊断体征，但这些体征偶尔可能在患者回国数年之后才出现。治疗采用乙胺嗪和苏拉明；文中描述了它们的用法及副作用，并列举了2例因治疗不当导致严重反应的病例。
