6-O-取代白屈菜碱衍生物对中枢神经系统作用的初步评价。
Preliminary evaluation of CNS effects of 6-O-substituted chelidonine derivatives.
作者信息
Jagiełło-Wójtowicz Ewa, Chodkowska Anna, Gadzikowska Maria, Chojecka-Koryn Ewa, Grynkiewicz Grzegorz
机构信息
Department of Toxicology, Medical University, 7 Chodźki Str., 20-093 Lublin. EwaFarmèskulap.am.lublin.pl
出版信息
Acta Pol Pharm. 2003 Mar-Apr;60(2):133-8.
PMID:13678323
Abstract
Eleven new derivatives of chelidonine I, obtained by functionalization of the alkaloid hydroxyl group, have been tested for CNS activity in mice exhibiting statistically significant effects.
摘要
通过对生物碱羟基进行官能化得到的11种白屈菜碱I的新衍生物，已在小鼠身上进行了中枢神经系统活性测试，显示出具有统计学意义的效果。
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