Sharma P, Bomireddy R, Phillips S
Department of Orthopaedic Surgery, King's College Hospital, Denmark Hill, London SE5 9RS, UK.
Eur J Clin Microbiol Infect Dis. 2003 Oct;22(10):615-8. doi: 10.1007/s10096-003-1000-9. Epub 2003 Sep 12.
The aim of the study presented here was to record the incidence and outcome of Clostridium difficile-associated diarrhoea in patients undergoing surgery for intertrochanteric femoral fractures. Between January 2000 and June 2001, a total of 239 patients who underwent surgery after sustaining an intertrochanteric femoral fracture were included in the study. Seventeen patients developed Clostridium difficile-associated diarrhoea (incidence risk, 7.1%), and six patients died after developing the condition (case fatality rate, 35%). Thus, Clostridium difficile-associated diarrhoea was found to cause significant morbidity and mortality after surgery for intertrochanteric femoral fractures, and antibiotics should be used judiciously in this group of patients.
本研究的目的是记录接受股骨粗隆间骨折手术患者中艰难梭菌相关性腹泻的发生率及转归。在2000年1月至2001年6月期间，共有239例股骨粗隆间骨折后接受手术的患者纳入本研究。17例患者发生艰难梭菌相关性腹泻（发病风险为7.1%），其中6例患者在发生该疾病后死亡（病死率为35%）。因此，发现艰难梭菌相关性腹泻在股骨粗隆间骨折手术后可导致显著的发病率和死亡率，在这组患者中应谨慎使用抗生素。
