来自澳洲邓纳利草的醉茄内酯苷

Withanolide glycosides from Dunalia australis.

作者信息

Lischewski M, Hang N T, Porzel A, Adam G, Massiot G, Lavaud C

机构信息

Institute of Plant Biochemistry, Halle/Saale, Germany.

出版信息

Phytochemistry. 1992 Mar;31(3):939-42. doi: 10.1016/0031-9422(92)80043-e.

DOI:10.1016/0031-9422(92)80043-e

PMID:1368042

Abstract

Four new withanolide glycosides, (20R,22R)-O-(3)-[beta-D- xylopyranosyl(1----3), beta-D-xylopyranosyl(1----4)]-beta-D-glucopyranosyl-3 beta,20-dihydroxy-1 alpha-acetoxy-witha-5,24-dienolide, (20R,22R)-O-(3)-[beta-D-xylopyranosyl(1----3), beta-D-glucopyranosyl(1----4)]-beta-D-glucopyranosyl-3 beta,20-dihydroxy-1 alpha-acetoxy-witha-5,24-dienolide, (20R,22R)-O-(3)-[beta-D- glucopyranosyl(1----3), beta-D-glucopyranosyl(1----4)]-beta-D-glucopyranosyl- 3 beta,20-dihydroxy-1 alpha-acetoxy-witha-5,24-dienolide and (20R,22R)-O-(3)-[beta-D-glucopyranosyl(1----3), beta-D- glucopyranosyl(1----4)]-beta-D-glucopyranosyl-3 beta, 12 beta,20-trihydroxy- 1 alpha,acetoxy-witha-5,24-dienolide, named dunawithanines C, D, E and F, respectively, were isolated from Dunalia australis. Their structures were elucidated on the basis of spectral and chemical evidence, especially NMR data of the peracetates.

摘要

从澳洲邓纳利草（Dunalia australis）中分离出四种新的醉茄内酯糖苷，分别命名为杜纳醉茄碱C、D、E和F，即(20R,22R)-O-(3)-[β-D-吡喃木糖基(1→3),β-D-吡喃木糖基(1→4)]-β-D-吡喃葡萄糖基-3β,20-二羟基-1α-乙酰氧基-威斯塔-5,24-二烯醇内酯、(20R,22R)-O-(3)-[β-D-吡喃木糖基(1→3),β-D-吡喃葡萄糖基(1→4)]-β-D-吡喃葡萄糖基-3β,20-二羟基-1α-乙酰氧基-威斯塔-5,24-二烯醇内酯、(20R,22R)-O-(3)-[β-D-吡喃葡萄糖基(1→3),β-D-吡喃葡萄糖基(1→4)]-β-D-吡喃葡萄糖基-3β,20-二羟基-1α-乙酰氧基-威斯塔-5,24-二烯醇内酯和(20R,22R)-O-(3)-[β-D-吡喃葡萄糖基(1→3),β-D-吡喃葡萄糖基(1→4)]-β-D-吡喃葡萄糖基-3β,12β,20-三羟基-1α-乙酰氧基-威斯塔-5,24-二烯醇内酯。它们的结构是根据光谱和化学证据，特别是过乙酸酯的核磁共振数据确定的。