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Binding of low molecular mass compounds to proteins studied by liquid chromatographic techniques.

作者信息

Cserháti Tibor, Forgács Esther, Deyl Zdenek, Miksik Iran, Echardt Adam

机构信息

Institute of Chemistry, Chemical Research Center, Hungarian Academy of Sciences, PO Box 17, 1525 Budapest, Hungary.

出版信息

Biomed Chromatogr. 2003 Sep;17(6):353-60. doi: 10.1002/bmc.266.

DOI:10.1002/bmc.266
PMID:13680844
Abstract

The newest achievements in the application of miscellaneous liquid chromatographic techniques such as size-exclusion, ion-exchange and reversed-phase high-performance liquid chromatography, and thin-layer chromatography for the elucidation of the various aspects of the binding of ligands to proteins are compiled and briefly discussed. Examples of employment in pharmaceutical and clinical chemistry, drug design, enzyme kinetic studies and environmental protection are presented.

摘要

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