用青霉胺治疗泛发性硬斑病的患者发生天疱疮。

Arch Dermatol. 1976 Sep;112(9):1308-9.

A 56-year-old woman with generalized morphea was treated with penicillamine. Four months after commencing treatment, she developed an eruption clinically, histologically, and immunopathologically consistent with pemphigus. The eruption disappeared following withdrawal of the drug. It is suggested that penicillamine initiated epidermal damage.

一名56岁的泛发性硬斑病女性患者接受了青霉胺治疗。开始治疗四个月后，她出现了临床上、组织学上和免疫病理学上与天疱疮相符的皮疹。停药后皮疹消失。提示青霉胺引发了表皮损伤。