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感染性核酸的光动力失活

Photodynamic inactivation of infectious nucleic acid.

作者信息

CHESSIN M

出版信息

Science. 1960 Dec 16;132(3442):1840-1. doi: 10.1126/science.132.3442.1840.

DOI:10.1126/science.132.3442.1840
PMID:13692932
Abstract

Tobacco mosaic virus-infectious nucleic acid causes a color shift when combined with acridine orange, methylene blue, and safranine. A high concentration of acridine orange inactivates infectious nucleic acid even in darkness, while a mixture of nucleic acid with a low concentration of the dye must be exposed to visible light prior to inoculation for inactivation to occur.

摘要

烟草花叶病毒感染性核酸与吖啶橙、亚甲蓝和番红结合时会引起颜色变化。即使在黑暗中，高浓度的吖啶橙也会使感染性核酸失活，而核酸与低浓度染料的混合物在接种前必须暴露于可见光下才能发生失活。

相似文献

1
Photodynamic inactivation of infectious nucleic acid.感染性核酸的光动力失活
Science. 1960 Dec 16;132(3442):1840-1. doi: 10.1126/science.132.3442.1840.
2
Recovery of infectious nucleic acid from tobacco mosaic virus inactivated by antibody.从被抗体灭活的烟草花叶病毒中回收传染性核酸。
Nature. 1959 Nov 28;184(Suppl 22):1732-3. doi: 10.1038/1841732a0.
3
Distribution of adenylic acid residues in nucleic acid of tobacco mosaic virus.烟草花叶病毒核酸中腺苷酸残基的分布
Biochim Biophys Acta. 1960 Aug 12;42:365-6. doi: 10.1016/0006-3002(60)90807-6.
4
Structural differences in the nucleic acids of some tobacco mosaic virus strains. II. Di- and tri-nucleotides in ribonuclease digests.某些烟草花叶病毒株系核酸的结构差异。II. 核糖核酸酶消化产物中的二核苷酸和三核苷酸
Biochim Biophys Acta. 1959 Apr;32:386-92. doi: 10.1016/0006-3002(59)90611-0.
5
Evidence for association of tobacco rattle virus nucleic acid with a cell component.烟草脆裂病毒核酸与一种细胞成分相关联的证据。
Nature. 1962 Jan 6;193:49-52. doi: 10.1038/193049a0.
6
[A method of histochemical detection of nucleic acids with the application of ribonuclease and a mixture of methyl green rhodamine 6Zh].
Arkh Patol. 1959;21(8):77-8.
7
Degradation of tobacco mosiac virus nucleic acid with micrococcal phosphodiesterase.用微球菌磷酸二酯酶降解烟草花叶病毒核酸。
Biochim Biophys Acta. 1959 Nov;36:132-42. doi: 10.1016/0006-3002(59)90077-0.
8
The infectivity and inactivation of nucleic acid preparations from tobacco mosaic virus.烟草花叶病毒核酸制剂的感染性与失活
J Gen Microbiol. 1959 Oct;21:438-56. doi: 10.1099/00221287-21-2-438.
9
[Method of isolation of free infectious nucleic acid in a plant infected with tobacco mosaic virus].
C R Hebd Seances Acad Sci. 1960 Oct 24;251:1843-4.
10
Study on the resonance light-scattering spectrum of anionic dye xylenol orange-cetyltrimethylammonium-nucleic acids system and determination of nucleic acids at nanogram levels.阴离子染料二甲酚橙-十六烷基三甲基铵-核酸体系的共振光散射光谱研究及纳克级核酸的测定
Spectrochim Acta A Mol Biomol Spectrosc. 2005 Jul;61(9):2215-20. doi: 10.1016/j.saa.2004.08.023.

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J Enzyme Inhib Med Chem. 2017 Dec;32(1):908-916. doi: 10.1080/14756366.2017.1335310.
2
Photodynamic inactivation of newcastle disease virus with acridine orange.吖啶橙对新城疫病毒的光动力灭活作用
Appl Microbiol. 1967 Nov;15(6):1452-5. doi: 10.1128/am.15.6.1452-1455.1967.
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[The photodynamic effect of thiopyronin on nucleic acids].[硫代吡咯宁对核酸的光动力效应]
Biophysik. 1966;3(3):241-8. doi: 10.1007/BF01190625.