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吖啶橙对新城疫病毒的光动力灭活作用

Photodynamic inactivation of newcastle disease virus with acridine orange.

作者信息

Frank G H, Foster J W

机构信息

Department of Microbiology and Preventive Medicine, School of Veterinary Medicine, University of Georgia Athens, Georgia 30602.

出版信息

Appl Microbiol. 1967 Nov;15(6):1452-5. doi: 10.1128/am.15.6.1452-1455.1967.

DOI:10.1128/am.15.6.1452-1455.1967
PMID:16349764
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC547231/
Abstract

Newcastle disease virus in allantoamnionic fluid was photosensitized with acridine orange, and then photodynamically inactivated. The inactivation rate was directly proportional to light intensity and to dye concentrations up to a level of approximately 100 to 200 mug/ml. Inactivation occurred at approximately an exponential rate for the first 4.5 log(10) units of virus, and then continued at a decreasing rate.

摘要

将尿囊羊水中的新城疫病毒用吖啶橙进行光敏化处理,然后进行光动力灭活。灭活率与光强度以及染料浓度直接成正比,直至染料浓度达到约100至200微克/毫升的水平。在病毒最初的4.5个对数(10)单位中,灭活以近似指数速率发生,然后以递减速率继续。

相似文献

1
Photodynamic inactivation of newcastle disease virus with acridine orange.吖啶橙对新城疫病毒的光动力灭活作用
Appl Microbiol. 1967 Nov;15(6):1452-5. doi: 10.1128/am.15.6.1452-1455.1967.
2
Oxygen radicals mediate cell inactivation by acridine dyes, fluorescein, and lucifer yellow CH.氧自由基介导吖啶染料、荧光素和路西法黄CH引起的细胞失活。
Photochem Photobiol. 1987 Jul;46(1):45-53. doi: 10.1111/j.1751-1097.1987.tb04734.x.
3
Photodynamic inactivation of newcastle disease virus with acridine orange.吖啶橙对新城疫病毒的光动力灭活作用
Appl Microbiol. 1968 Mar;16(3):547. doi: 10.1128/am.16.3.547-547.1968.
4
Photodynamic effects of dyes on bacteria. II. Genetic effects of broad-spectrum visible light in the presence of acridine dyes and methylene blue in chemostat cultures of Escherichia coli.染料对细菌的光动力效应。II. 在恒化器培养的大肠杆菌中,吖啶染料和亚甲蓝存在时广谱可见光的遗传效应。
Mutat Res. 1979 Jan;59(1):1-13. doi: 10.1016/0027-5107(79)90190-8.
5
[Lethal and mutagenic photodynamic effect of acridine orange on bacteriophage cd].[吖啶橙对噬菌体cd的致死和诱变光动力效应]
Genetika. 1976;12(7):109-18.
6
Acridine orange-mediated photodamage of microsomal- and lysosomal fractions.吖啶橙介导的微粒体和溶酶体组分的光损伤
Virchows Arch B Cell Pathol Incl Mol Pathol. 1989;56(4):247-57. doi: 10.1007/BF02890023.
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Photodynamic inactivation of bladder cancer cells (MGH-U1) sensitized with acridine orange and irradiated by argon laser.用吖啶橙致敏并用氩激光照射对膀胱癌细胞(MGH-U1)进行光动力灭活。
Tohoku J Exp Med. 1984 Nov;144(3):265-71. doi: 10.1620/tjem.144.265.
8
Photodynamic inactivation of infectious nucleic acid.感染性核酸的光动力失活
Science. 1960 Dec 16;132(3442):1840-1. doi: 10.1126/science.132.3442.1840.
9
[Photodynamic effect of quinacrine on bacteria].[喹吖因对细菌的光动力效应]
Z Allg Mikrobiol. 1979;19(3):181-5.
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Mechanisms of photodynamic inactivation of acridine orange-sensitized transfer RNA: participation of singlet oxygen and base damage leading to inactivation.吖啶橙敏化转运核糖核酸的光动力失活机制:单线态氧的参与和导致失活的碱基损伤。
J Radiat Res. 1986 Dec;27(4):339-51. doi: 10.1269/jrr.27.339.

本文引用的文献

1
Inactivation of viruses by the photodynamic action of toluidine blue.通过甲苯胺蓝的光动力作用使病毒失活。
J Immunol. 1960 May;84:480-4.
2
KINETICS OF THE INACTIVATION OF VIRUSES.病毒灭活动力学
Bacteriol Rev. 1964 Jun;28(2):150-63. doi: 10.1128/br.28.2.150-163.1964.
3
Cytochemical and fluorescent antibody studies on the growth of poliovirus in tissue culture.关于脊髓灰质炎病毒在组织培养中生长的细胞化学和荧光抗体研究。
Tex Rep Biol Med. 1961;19:106-22.
4
Photodynamic inactivation of infectious nucleic acid.感染性核酸的光动力失活
Science. 1960 Dec 16;132(3442):1840-1. doi: 10.1126/science.132.3442.1840.
5
Vital staining of blood parasites with acridine orange.用吖啶橙对血液寄生虫进行活体染色。
J Parasitol. 1958 Dec;44(6):588-94.
6
Fluorescence microscopy in the study of nucleic acids; histochemical observations on cellular and virus nucleic acids.核酸研究中的荧光显微镜术;关于细胞和病毒核酸的组织化学观察。
Nature. 1957 Dec 14;180(4598):1335-6. doi: 10.1038/1801335a0.