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模具中的有丝分裂金：曲霉遗传学与有丝分裂生物学

Mitotic gold in a mold: Aspergillus genetics and the biology of mitosis.

作者信息

Morris N R, Enos A P

机构信息

Department of Pharmacology, University of Medicine and Dentistry of New Jersey, Piscataway 08854-5635, USA.

出版信息

Trends Genet. 1992 Jan;8(1):32-7. doi: 10.1016/0168-9525(92)90022-v.

DOI:10.1016/0168-9525(92)90022-v
PMID:1369734
Abstract

The analysis of fungal mutants has had an extraordinary impact on our understanding of the biochemistry and regulation of mitosis. In this article we review the contribution of work on the filamentous fungus Aspergillus nidulans to the molecular genetics of mitosis.

摘要

对真菌突变体的分析对我们理解有丝分裂的生物化学和调控产生了非凡的影响。在本文中，我们综述了关于丝状真菌构巢曲霉的研究工作对有丝分裂分子遗传学的贡献。

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Mitotic gold in a mold: Aspergillus genetics and the biology of mitosis.模具中的有丝分裂金：曲霉遗传学与有丝分裂生物学
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2
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The Set1/COMPASS histone H3 methyltransferase helps regulate mitosis with the CDK1 and NIMA mitotic kinases in Aspergillus nidulans.Set1/COMPASS组蛋白H3甲基转移酶与构巢曲霉中的CDK1和NIMA有丝分裂激酶共同帮助调节有丝分裂。
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Mitotic histone H3 phosphorylation by the NIMA kinase in Aspergillus nidulans.构巢曲霉中NIMA激酶介导的有丝分裂组蛋白H3磷酸化作用
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Cell Biology. Never-in-mitosis in mitosis.
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Activation of the nimA protein kinase plays a unique role during mitosis that cannot be bypassed by absence of the bimE checkpoint.nimA蛋白激酶的激活在有丝分裂过程中发挥着独特作用，这种作用不能因缺乏bimE检查点而被绕过。
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The polo-like kinase PLKA is required for initiation and progression through mitosis in the filamentous fungus Aspergillus nidulans.在丝状真菌构巢曲霉中，polo样激酶PLKA是有丝分裂起始和进程所必需的。
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