脉孢菌中精氨酸和嘧啶的生物合成

Arginine and pyrimidine biogenesis in Neurospora.

作者信息

FAIRLEY J L, ADAMS A B

出版信息

Science. 1961 Aug 18;134(3477):471-2. doi: 10.1126/science.134.3477.471.

DOI:10.1126/science.134.3477.471

Abstract

The growth-promoting activity of propionic acid and related compounds for the pyrimidine-less strain, Neurospora crassa 1298, is markedly inhibited by arginine. The data suggest that arginine exerts an inhibitory effect upon or represses the synthesis of an enzyme involved in pyrimidine formation.

摘要

丙酸及相关化合物对嘧啶缺陷型菌株粗糙脉孢菌1298的促生长活性受到精氨酸的显著抑制。数据表明，精氨酸对参与嘧啶形成的一种酶的合成产生抑制作用或抑制其合成。