GRIN E I
Bull World Health Organ. 1961;24(2):229-38.
It has been recognized for many years that Africa contains a very large reservoir of endemic treponematoses, and all information on the foci of infection contributes to the goal of elimination of these diseases as public health problems.In 1959 the author undertook, at the request of the Sudanese Government, a number of pilot surveys in areas where the endemic treponematoses were thought to be prevalent. From the information acquired in these surveys and from official data it is clear that yaws and endemic syphilis are a major problem of public health in the Sudan. It is estimated that some 5 million people in six provinces are at risk, and that about 20% of the population in an area of 1 543 000 km(2) suffer from one or the other of the two diseases in the active clinical stage.In some localities yaws was found to be prevalent, and in some endemic syphilis. In others, the two infections were seen to co-exist; and it is suggested that, since little is known of the extent to which one infection confers protection against the other, the situation in the Sudan provides a perhaps unique opportunity for scientific studies of the interrelationship of these two diseases and their possible relationship with venereal syphilis.Another interesting finding, worthy of further investigation, was that mucous lesions occurred only in areas where syphilis was present and not where yaws alone was prevalent.
多年来人们已经认识到,非洲存在大量地方性密螺旋体病疫源地,所有关于感染病灶的信息都有助于实现将这些疾病作为公共卫生问题予以消除的目标。1959年,作者应苏丹政府的要求,在认为地方性密螺旋体病流行的地区进行了一些试点调查。从这些调查获得的信息以及官方数据来看,雅司病和地方性梅毒显然是苏丹公共卫生的一个主要问题。据估计,六个省份约500万人面临风险,在面积达154.3万平方公里的地区,约20%的人口患有这两种疾病中的一种处于临床活动期。在一些地方发现雅司病流行,在一些地方地方性梅毒流行。在其他地方,发现这两种感染并存;有人提出,由于对一种感染对另一种感染的保护程度了解甚少,苏丹的情况为科学研究这两种疾病的相互关系以及它们与性病梅毒可能的关系提供了一个或许独特的机会。另一个值得进一步研究的有趣发现是,黏膜病变仅发生在有梅毒的地区,而在仅流行雅司病的地区则未出现。