Gilliland S E, Speck M L
Appl Environ Microbiol. 1977 Jan;33(1):15-8. doi: 10.1128/aem.33.1.15-18.1977.
Lactobacillus species normally found in the intestinal tract of humans varied in the ability to deconjugate bile acids, whereas laboratory strains of Lactobacillus acidophilus deconjugated both glycocholate and taurocholate. All isolates of L. acidophilus from human feces deconjugated taurocholate, whereas only one of six deconjugated glycocholate. None of 13 isolates identified as L. casei deconjugated taurocholate, whereas 9 deconjugated glycocholate. The deconjugating system of L. acidophilus appeared to be constitutive, required low oxidation-reduction potential, and was most active at pH 6. No degradation beyond deconjugation was detected.
通常在人类肠道中发现的乳酸杆菌属在胆汁酸去结合能力方面存在差异，而嗜酸乳杆菌的实验室菌株能使甘氨胆酸盐和牛磺胆酸盐都发生去结合。从人类粪便中分离出的所有嗜酸乳杆菌菌株都能使牛磺胆酸盐去结合，而六株中只有一株能使甘氨胆酸盐去结合。鉴定为干酪乳杆菌的13株分离物中没有一株能使牛磺胆酸盐去结合，而有9株能使甘氨胆酸盐去结合。嗜酸乳杆菌的去结合系统似乎是组成型的，需要低氧化还原电位，并且在pH 6时最活跃。未检测到除去结合之外的降解情况。
