Berndt W O
Environ Health Perspect. 1976 Jun;15:73-88. doi: 10.1289/ehp.761573.
A detailed discussion of the tissue slice technique for evaluation of transport phenomena is presented. Information is given concerning the preparation of tissue slices and the advantages of this procedure over corresponding in vivo techniques. In addition, the relationship of the in vitro renal transport of organic substances to in vivo renal function is discussed in detail. Finally, certain pitfalls related to in vitro slice transport studies are presented.
本文详细讨论了用于评估转运现象的组织切片技术。给出了有关组织切片制备的信息以及该方法相对于相应体内技术的优势。此外,还详细讨论了有机物质的体外肾脏转运与体内肾功能之间的关系。最后,介绍了与体外切片转运研究相关的一些陷阱。