HORTON-SMITH C, BEATTIE J, LONG P L
Immunology. 1961 Apr;4(2):111-21.
Infections were produced in patent caeca by administering oocysts of to fowls in which one caecum was ligated. The caeca were later challenged with sporozoites and it was found that a resistance to infection had been acquired by the previously uninfected ligated caeca. The observations indicate that resistance to caecal coccidiosis develops in areas not previously exposed to parasitism by . It is suggested that the immunity acquired by the ligated caeca is mediated through the circulation either by humoral antibodies or by lymphoid cells, or by a combination of both.
通过向一侧盲肠被结扎的家禽投喂球虫卵囊，在开放的盲肠中引发感染。随后，用子孢子对盲肠进行攻击，发现先前未感染的结扎盲肠已获得对感染的抵抗力。这些观察结果表明，对盲肠球虫病的抵抗力在以前未受到寄生虫寄生的区域中形成。有人提出，结扎盲肠获得的免疫力是通过体液抗体或淋巴细胞，或两者的组合经循环介导的。
