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辐射灭菌

Radiation sterilization.

作者信息

DARMADY E M, HUGHES K E, BURT M M, FREEMAN B M, POWELL D B

出版信息

J Clin Pathol. 1961 Jan;14(1):55-8. doi: 10.1136/jcp.14.1.55.

DOI:10.1136/jcp.14.1.55
PMID:13719781
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC480158/
Abstract

The sterilization by radiation of disposable medical items has been investigated. Various vegetative and spore-bearing bacteria have been irradiated and results indicate that 2.5 Mrad can be recommended to give a high degree of sterility. Spores of B. pumilus (E.601) showed such resistance that it might be a suitable test organism for determining the efficiency of a radiation treatment. A high standard of packaging must be demanded for pre-sterilized products.

摘要

对一次性医疗用品的辐射灭菌进行了研究。对各种有繁殖能力的细菌和产孢细菌进行了辐照,结果表明,推荐采用2.5兆拉德的剂量以实现高度无菌。短小芽孢杆菌(E.601)的孢子显示出很强的抗性,它可能是确定辐射处理效果的合适测试生物。对于预灭菌产品,必须要求高标准的包装。

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本文引用的文献

1
Thermal death-time of spores in dry heat in relation to sterilisation of instruments and syringes.与器械和注射器灭菌相关的干热条件下孢子的热死时间
Lancet. 1958 Oct 11;2(7050):766-9. doi: 10.1016/s0140-6736(58)91477-6.
2
The sterilization of dressings.敷料的灭菌
J Clin Pathol. 1957 Nov;10(4):299-306. doi: 10.1136/jcp.10.4.299.
3
Relative resistances of micro-organisms to cathode rays. III. Bacterial spores.微生物对阴极射线的相对抗性。III. 细菌芽孢
Appl Microbiol. 1956 May;4(3):149-52. doi: 10.1128/am.4.3.149-152.1956.
4
A medium promoting rapid quantitative sporulation in Clostridium perfringens.一种促进产气荚膜梭菌快速定量产芽孢的培养基。
J Bacteriol. 1956 Apr;71(4):495-6. doi: 10.1128/jb.71.4.495-496.1956.