用于监测辐射灭菌的短小芽孢杆菌芽孢试纸条的稳定性
Stability of Bacillus pumilus spore strips used for monitoring radiation sterilization.
作者信息
Prince H N
出版信息
Appl Environ Microbiol. 1976 Jun;31(6):999-1000. doi: 10.1128/aem.31.6.999-1000.1976.
Abstract
Dried Bacillus pumilus spore strips had a stable D-value of 0.17 to 0.18 Mrad after 1 year at 5 or 25 C, but resistance was lost at 35 C. Refrigeration did not have an adverse effect on resistance to irradiation. The presence of water at the time of initial preparation increased this resistance to 0.23 to 0.25 Mrad. Proper drying is essential to achieve reproducible results in sterility tests using USP-type biological indicators.
摘要
干燥的短小芽孢杆菌芽孢条在5℃或25℃下保存1年后，其D值稳定在0.17至0.18兆拉德，但在35℃下抗性丧失。冷藏对辐射抗性没有不利影响。初始制备时存在水分会使这种抗性提高到0.23至0.25兆拉德。在使用USP型生物指示剂进行无菌测试时，适当干燥对于获得可重复的结果至关重要。
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