人嗜T淋巴细胞病毒I型相关脊髓病（HAM）中脊髓上行传导束的生理功能

Physiological functions of the ascending spinal tracts in HTLV-I-associated myelopathy (HAM).

作者信息

Kakigi R, Kuroda Y, Takashima H, Endo C, Neshige R, Shibasaki H

机构信息

Department of Internal Medicine, Saga Medical School, Japan.

出版信息

Electroencephalogr Clin Neurophysiol. 1992 Mar-Apr;84(2):110-4. doi: 10.1016/0168-5597(92)90015-4.

DOI:10.1016/0168-5597(92)90015-4

PMID:1372225

Abstract

Physiological functions of the spinothalamic tract (STT) and the posterior column (PC) were studied in 19 Japanese patients with HTLV-I-associated myelopathy (HAM). The former was evaluated by pain-related somatosensory evoked potentials (SEPs) following CO2 laser stimulation, and the latter by conventional SEPs following electrical stimulation. Conduction velocity of STT and PC was significantly decreased in 9 and 14 patients, respectively, and more than half of them showed no clinical impairment of sensations (subclinical abnormality).

摘要

对19例成人T细胞白血病病毒I型相关脊髓病（HAM）日本患者的脊髓丘脑束（STT）和后柱（PC）的生理功能进行了研究。前者通过二氧化碳激光刺激后的疼痛相关体感诱发电位（SEP）进行评估，后者通过电刺激后的传统SEP进行评估。STT和PC的传导速度分别在9例和14例患者中显著降低，其中超过一半的患者没有感觉的临床损害（亚临床异常）。