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甲氧苄啶磺胺甲恶唑联合用药在儿童中的疗效与耐受性(作者译)

[Efficacy and tolerance of trimethoprim sulfamoxole combination in childhood (author's transl)].

作者信息

Helwig H, Bulla M, Sitzmann W, Schreier K, Loh K, Wodetzky A

出版信息

Klin Padiatr. 1976 Nov;188(6):518-27.

PMID:137345
Abstract

CN 3123 was tested in 4 hospitals on 257 children, 218 of whom were included in the evaluation of the success of therapy. It was administered for the treatment of urinary tract infections (n = 125), bronchial infections (n = 24), intestinal infections (n = 25) and ENT infections (n = 37). The results indicated that, with a failure rate of only 7%, the drug was successfully employed. Tolerance to the medicament was good. Vomiting occurred in 7 children (2.7%) and allergic skin reactions were observed in 6 children (2.3%). A comparative study of CN 3123 and Co-trimoxazole showed the same efficacy and tolerance for both medicaments.

摘要

CN 3123在4家医院对257名儿童进行了测试,其中218名儿童纳入治疗成功率评估。它被用于治疗尿路感染(n = 125)、支气管感染(n = 24)、肠道感染(n = 25)和耳鼻喉感染(n = 37)。结果表明,该药物的成功率仅为7%,使用成功。对该药物的耐受性良好。7名儿童(2.7%)出现呕吐,6名儿童(2.3%)出现过敏性皮肤反应。CN 3123与复方新诺明的对比研究表明,两种药物的疗效和耐受性相同。

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