雌二醇减少放射性硫酸盐掺入大鼠的软骨和主动脉。
Estradiol reduces incorporation of radioactive sulfate into cartilage and aortas of rats.
作者信息
PRIEST R E, KOPLITZ R M, BENDITT E P
出版信息
J Exp Med. 1960 Jul 1;112(1):225-36. doi: 10.1084/jem.112.1.225.
Abstract
Estradiol in large amounts reduces the incorporation of radioactive sulfate into cartilage and aortas of rats. This reduction becomes apparent within 3 days for cartilage and 3 weeks for aorta. The effect is not mediated through suppression of testosterone secretion and the hypophysis is not necessary for the effect to be demonstrated. The thoracic segment of aortas from normal rats incorporates more sulfate than does the abdominal segment and this difference is reduced following the administration of estradiol.
摘要
大量的雌二醇会减少放射性硫酸盐掺入大鼠的软骨和主动脉。这种减少在软骨中3天内明显，在主动脉中3周内明显。该作用不是通过抑制睾酮分泌介导的，并且该作用的表现不需要垂体。正常大鼠主动脉的胸段比腹段掺入更多的硫酸盐，给予雌二醇后这种差异会减小。
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