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5-羟色胺对水蛭（医用水蛭）背肌的影响。

Effects of 5-hydroxytryptamine on the dorsal muscle of the leech (Hirudo medicinalis).

作者信息

SCHAIN R J

出版信息

Br J Pharmacol Chemother. 1961 Jun;16(3):257-61. doi: 10.1111/j.1476-5381.1961.tb01085.x.

DOI:10.1111/j.1476-5381.1961.tb01085.x
PMID:13747232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1482034/
Abstract

5-Hydroxytryptamine has an inhibiting effect on the leech muscle. It reduces the contractions produced by acetylcholine or nicotine and accelerates the relaxation of the muscle when these substances are washed out. This acceleration of relaxation allows a more rapid assay of acetylcholine in this preparation.

摘要

5-羟色胺对水蛭肌肉有抑制作用。它能减少乙酰胆碱或尼古丁引起的收缩，并在这些物质被洗脱时加速肌肉的松弛。这种松弛的加速使得在该制剂中能更快速地测定乙酰胆碱。

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本文引用的文献

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Effects of acetylcholine and 5-hydroxytryptamine on the contraction of a molluscan smooth muscle.乙酰胆碱和5-羟色胺对软体动物平滑肌收缩的影响。
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The quantitative distribution of 5-hydroxytryptamine in the invertebrates, especially in their nervous systems.5-羟色胺在无脊椎动物中的定量分布，尤其是在其神经系统中的分布。
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Neurohumors and other pharmacologically active substances in cerebrospinal fluid: a review of the literature.脑脊液中的神经体液及其他药理活性物质：文献综述
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Serotonin as a possible neurohumoral agent; evidence obtained in lower animals.血清素作为一种可能的神经体液介质；在低等动物身上获得的证据。
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Responses of a molluscan smooth muscle to acetylcholine and 5-hydroxytryptamine.软体动物平滑肌对乙酰胆碱和5-羟色胺的反应。
J Cell Comp Physiol. 1954 Aug;44(1):141-63. doi: 10.1002/jcp.1030440112.